Iron-Catalyzed Transfer Hydrogenation of Allylic Alcohols with Isopropanol - data

Herein, we report an iron-catalyzed transfer hydrogenation of allylic alcohols. The operationally simple protocol
employs a well-defined bench stable (cyclopentadienone)iron(0) carbonyl complex as precatalyst in combination with K2CO3 (4 mol %) and isopropanol as the hydrogen donor. A diverse range of allylic alcohols undergo transfer hydrogenation to form the corresponding alcohols in good yields (33 examples, up to 83% isolated yield). The scope and limitations of the method have been investigated in addition to experiments that shed light upon the reaction mechanism.

Analysis of reaction products from this methodology resulted in the following data:

1H, 19F and 13C NMR raw data files

IR spectra

High-Resolution Mass Spectrography spectra.