Iron-Catalyzed Borrowing-Hydrogen β‐C(sp3)‐Methylation of Alcohols

<p>Herein we report the iron-catalyzed <em>b-C</em>(sp3)-methylation of primary alcohols using methanol as a C1 building block. This borrowing hydrogen approach employs a well-defined bench stable (cyclopentadienone)iron(0) carbonyl complex as precatalyst (5 mol %) and enables a diverse selection of substituted 2-arylethanols to undergo <em>b-C</em>(sp3)-methylation in good isolated yields (24 examples, 65% average yield).</p><p>Analysis of reaction products from this methodology resulted in the following data:</p><p>1H, 19F and 13C NMR raw data files</p><p>IR spectra<br></p><p>High resolution mass spectrometry spectra.    </p><p>Research results based upon these data are published at http://doi.org/10.1021/acscatal.9b02461.</p>