Genome-wide association studies for myopia in related and unrelated individuals

A GWAS for myopia was performed in unrelated individuals from UK Biobank (n = 25,804 cases; n = 40,969 controls) conducted using PLINK v2.

A GWAS for myopia was performed in related individuals from UK Biobank (n = 35,531 cases; n = 57,505 controls) conducted using SAIGE/GATE.

FILE INDEX:

SNP = Variant identifier

CHR = Chromosome on genome build GRCh37

POS = Position on genome build GRCh37

EFFECT_ALLELE = Effect allele

NON_EFFECT_ALLELE = Non-effect allele

OR = Odds ratio of outcome per copy of the risk allele

BETA = Effect size (log(OR) scale) of outcome per copy of the risk allele

SE = Standard error of effect size

P = P-value of effect