Genome-wide association studies for myopia in related and unrelated individuals

<p dir="ltr">A GWAS for myopia was performed in unrelated individuals from UK Biobank (n = 25,804 cases; n = 40,969 controls) conducted using PLINK v2.</p><p dir="ltr">A GWAS for myopia was performed in related individuals from UK Biobank (n = 35,531 cases; n = 57,505 controls) conducted using SAIGE/GATE.</p><p dir="ltr">FILE INDEX:</p><p dir="ltr">SNP = Variant identifier</p><p dir="ltr">CHR = Chromosome on genome build GRCh37</p><p dir="ltr">POS = Position on genome build GRCh37</p><p dir="ltr">EFFECT_ALLELE = Effect allele</p><p dir="ltr">NON_EFFECT_ALLELE = Non-effect allele</p><p dir="ltr">OR = Odds ratio of outcome per copy of the risk allele</p><p dir="ltr">BETA = Effect size (log(OR) scale) of outcome per copy of the risk allele</p><p dir="ltr">SE = Standard error of effect size</p><p dir="ltr">P = P-value of effect</p>