Electrochemical oxidative Z-selective C(sp2)–H chlorination of acrylamides - data

<p>An electrochemical method for the oxidative <em>Z</em>-selective C(sp²)–H chlorination of acrylamides has been developed. This catalyst and organic oxidant free method is applicable across various substituted tertiary acrylamides, and provides access to a broad range of synthetically useful <em>Z</em>-<em>b</em>-chloroacrylamides in good yields (22 examples, 73% average yield). The orthogonal derivatization of the products was demonstrated through chemoselective transformations and the electrochemical process was performed on gram scale in flow.</p><p>Analysis of reaction products from this methodology resulted in the following data:</p><p>1H, 19F and 13C NMR raw data files</p><p>IR spectra</p><p>High-Resolution Mass Spectrography spectra.<br></p><p>Research results based upon these data are published at https://doi.org/10.1039/D1CC05824J<br></p><p><br></p>