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Decoding Grey Matter - Meshes

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posted on 2025-10-31, 14:47 authored by Charlie Aird-RossiterCharlie Aird-Rossiter, Marco PalomboMarco Palombo
<p dir="ltr">The following meshes are associated with the paper 'Decoding Gray Matter: large-scale analysis of brain cell morphometry to inform microstructural modeling of diffusion MR signals'</p><p dir="ltr">Grey matter structure is a key focus in neuroscience, as cell morphology varies by type and can be affected by neurological conditions. Understanding these variations is essential for studying brain function and disease. Diffusion-weighted MRI (dMRI) is a powerful tool for examining cellular microstructure in vivo, but its accuracy depends on identifying which morphological features influence its measurements. Despite growing interest, no systematic report has defined key neural cell traits.</p><p dir="ltr">We analysed more than 11,800 3D cellular reconstructions, obtained from <a href="https://neuromorpho.org/" rel="noreferrer" target="_blank">Neuromorpho.org</a>, across three species and nine cell types, establishing reference values for critical traits. </p><p dir="ltr">To complement the statistical analysis, here we also provide high resolution 3D surface meshes representative of each cell type and species. For each cell type we provide 50 .ply meshes and the corresponding cellular skeleton saved as an .swc file. All meshes were meshed in blender using matlab scripts, which are publicly available on <a href="https://github.com/Charlie-Aird/Decoding-Grey-Matter" rel="noreferrer" target="_blank">github</a>. These meshes are fully compatible with Monte Carlo simulators, offering a valuable resource for the modelling community.</p>

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Data file formats

Meshes are saved as .ply files and the neural skeletons are saved as .swc files.

Specialist software required to view data files

The meshes can be used in any Monte Carlo Diffusion simulator (DiSimpy, MCDC, CAMINO...) that accept ply files as the bounding geometry.

Research Institute / Centre linked to data generation

  • CUBRIC: Cardiff University Brain Research Imaging Centre

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    School of Psychology

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