Amplifying Solventless Synthesis: One-pot Multistep Mechanochemical Synthesis of Fluorinated Pyrazolones

<p>A one-pot, two step mechanochemical synthesis process has been developed, of fluorinated pyrazolones. The experiments here have provided a logical approach to multistep solventless synthesis under milling conditions. This demonstrates the applicability of mechanochemical synthesis to multistep procedures.<br><br>Analysis of reaction products from this methodology resulted in the following data:<br>1H, 19F and 13C NMR raw data files<br>IR spectra<br>High-Resolution Mass Spectrography spectra.<br><br>Research results based upon these data are published as http://doi.org/10.3762/bjoc.13.189<br></p>